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World Journal of Biological and Pharmaceutical Research
Peer-Reviewed • ISSN: 2799-0338 • Impact Factor 7.8

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🌟 🧬 World Journal of Biological and Pharmaceutical Research (WJBPR) 🧬 🌟

Low-Cost Journal Publication | CrossRef DOI | Transparent Peer Review Process

International, Open Access, Peer-Reviewed, Multidisciplinary Journal in Biological and Pharmaceutical Sciences, Indexed in Major Databases, DOI Assignment (Crossref)

ISSN: 2799-0338 | Impact Factor: 7.8 | ESTD Year: 2021 | Charges 35 USD

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The role of 5´-nucleotidases in function of immune system cells

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  • The role of 5´-nucleotidases in function of immune system cells

AA Pepanyan, PA Ghazaryan * and SH Danelyan

CJsC "Center of Haematology named after prof. R.H. Yeolyan" MH RA.

Research Article
World Journal of Biological and Pharmaceutical Research, 2022, 02(01), 005–009.
Article DOI: 10.53346/wjbpr.2022.2.1.0133
DOI url: https://doi.org/10.53346/wjbpr.2022.2.1.0133

Received on 15 November 2021; revised on 24 January 2022; accepted on 26 January 2022
 

Disorder of purine metabolism, in particular the activity of 5'-nucleotidase, which is one of the key enzymes of the purine cycle, leads to functional inferiority of cells of the immune system. 5'-nucleotidase is considered a marker of the functional maturity of lymphocytes. In our opinion, research of activity of the enzyme at various immunodeficiency conditions can serve not only as additional prognostic criteria but also be essential help both at tactics choice and at an estimation of efficiency of therapy with purine analogs.
 

Purine nucleotides; 5´-nucleotidase; Immune system; Lymphoproliferative diseases

https://wjbpr.zealjournals.com/sites/default/files/fulltext_pdf/WJBPR-2021-0133…

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AA Pepanyan, PA Ghazaryan and SH Danelyan. The role of 5´-nucleotidases in function of immune system cells. World Journal of Biological and Pharmaceutical Research, 2022, 02(01), 005–009.Article DOI: https://doi.org/10.53346/wjbpr.2022.2.1.0133

Copyright © Author(s). All rights reserved. This article is published under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits use, sharing, adaptation, distribution, and reproduction in any medium or format, as long as appropriate credit is given to the original author(s) and source, a link to the license is provided, and any changes made are indicated.

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